Protease Inhibitors and Phosphatase Inhibitors
MilliporeSigma™ Calbiochem™ Caspase-1 Substrate VI, Fluorogenic
Fluorogenic caspase-1 substrate.
MilliporeSigma™ Calbiochem™ AP-1/NF-κB Dual Inhibitor, SP100030
A cell-permeable, non-toxic, conformationally restricted pyrimidinecarboxamide compound that acts as a potent, reversible T-cell specific inhibitor of both AP-1 and NF-κB transcriptional activation (IC50 = 50
MilliporeSigma™ Calbiochem™ AG 825
A potent, cell-premeable, reversible, substrate competitive, and selective inhibitor of HER2 (neu/ErbB2; IC50 = 0.35 μM) relative to HER1 (IC50 19 μM) autophosphorylation.
MilliporeSigma™ Calbiochem™ Nrf2 Activator IV, VSC2
A cell-permeable, potent Nrf-2 activator that stimulates HO-1 expression in murine microglial BV-2 cultures. Induces overall Nrf2 cellular accumulation and nuclear translocation.
MilliporeSigma™ Calbiochem™ InSolution™ PARP Inhibitor VIII, PJ34
The InSolution™ PARP Inhibitor VIII, PJ34 controls the biological activity of PARP. This small molecule/inhibitor is primarily used for Cell Structure applications.
MilliporeSigma™ Calbiochem™ JAK3 Inhibitor VIII, NSC114792
The JAK3 Inhibitor VIII, NSC114792 controls the biological activity of JAK3. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.
MilliporeSigma™ Calbiochem™ Thrombin Receptor Agonist
The Thrombin Receptor Agonist, also referenced under CAS 137339-65-2, controls the biological activity of Thrombin Receptor. This small molecule/inhibitor is primarily used for Activators/Inducers applications.
MilliporeSigma™ Calbiochem™ JNK Inhibitor III, Cell-Permeable
The JNK Inhibitor III, Cell-Permeable controls the biological activity of JNK. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.
MilliporeSigma™ Calbiochem™ MMP Inhibitor I
The MMP Inhibitor I controls the biological activity of MMP. This small molecule/inhibitor is primarily used for Protease Inhibitors applications.
MilliporeSigma™ Calbiochem™ Histone Deacetylase Inhibitor VIII
The Histone Deacetylase Inhibitor VIII, also referenced under CAS 1045792-66-2, controls the biological activity of Histone Deacetylase. This small molecule/inhibitor is primarily used for Cell Structure applications.
MilliporeSigma™ Calbiochem™ D-Amino Acid Oxidase Inhibitor II, CBIO
The D-Amino Acid Oxidase Inhibitor II, CBIO, also referenced under CAS 61977-29-5, controls the biological activity of D-Amino Acid Oxidase.
MilliporeSigma™ Calbiochem™ 5,7-Dichlorokynurenic Acid, Sodium Salt
A very potent, water-soluble antagonist of the NMDA receptors complex acting at the strychnine-insensitive glycine binding site (Ki = 79 nM
MilliporeSigma™ Calbiochem™ Sphingosine Kinase 1 Inhibitor, SKI-178
A cell-permeable pyrazolocarbohydrazide compound that acts as a potent, reversible, sphingosine competitive and ATP-non-competitive inhibitor of sphingosine kinase 1 (SphK1) activity with excellent selectivity over SphK2 (Ki
MilliporeSigma™ Calbiochem™ Ischemin
A cell-permeable azobenzene compound that reversibly targets CBP-BRD acetyl-lysine binding pocket with moderate selectivity over BAZ1B, PCAF, BRD4-1 and BAZ2B.
MilliporeSigma™ Calbiochem™ BLM Helicase Inhibitor, ML216
A cell-permeable pyridinyl-thiadiazolylurea compound that selectively blocks Bloom's syndrome protein (BLM) helicase activity of both full-length as well as truncated BLM636-1298 forms (IC50